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Trazodone can reliably and safely induce sedation and anxiolysis in dogs and cats, making it a useful pharmacologic agent beyond the treatment of behavior problems. Trazodone has been clinically used in both dogs and cats; however, its use has been more extensively researched in dogs for treating situational anxiety related to
• Separation
• Noise phobia (eg, fireworks, thunderstorms)
• Veterinary visits
• Hospitalization
• Travel
• Postoperative confinement
• Adjunct therapy used in combination with other psychopharmaceutical agents to treat anxiety-related behavioral
problems (eg, fearful behavior toward humans or other animals)